Dirk Geerts Selected Research

1- (4- (6- (2- (isopropylsulfonyl)phenylamino)- 9H- purin- 2- ylamino)- 3- ethoxyphenyl)piperidin- 4- ol

9/2013

Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs.

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Dirk Geerts Research Topics

Disease

34	Neoplasms (Cancer) 01/2022 - 11/2007
19	Neuroblastoma 01/2019 - 11/2007
7	Breast Neoplasms (Breast Cancer) 01/2021 - 10/2014
5	Carcinogenesis 01/2022 - 01/2014
5	Inflammation (Inflammations) 01/2019 - 06/2012
5	Neoplasm Metastasis (Metastasis) 01/2018 - 10/2014
4	Glioblastoma (Glioblastoma Multiforme) 11/2016 - 09/2010
2	Neuroinflammatory Diseases 01/2019 - 06/2012
2	Astrocytoma (Pilocytic Astrocytoma) 07/2014 - 07/2014
2	Glioma (Gliomas) 07/2014 - 07/2010
2	Leukemia 08/2013 - 01/2013
2	Multiple Sclerosis 02/2013 - 06/2012
1	Colorectal Neoplasms (Colorectal Cancer) 01/2022
1	Endometrial Neoplasms (Endometrial Cancer) 01/2022
1	Adenocarcinoma 12/2021
1	Atrioventricular Block 01/2020
1	Hematologic Neoplasms (Hematological Malignancy) 01/2020
1	Bradycardia 01/2020
1	Virus Diseases (Viral Diseases) 01/2019
1	Rheumatoid Arthritis 01/2019
1	Ulcerative Colitis 01/2019
1	Ischemia 09/2018
1	Necrosis 01/2018
1	Osteosarcoma (Osteogenic Sarcoma) 01/2018
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2017
1	Starvation 11/2016
1	Obesity 01/2016
1	Insulin Resistance 01/2016
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2016
1	Triple Negative Breast Neoplasms 10/2014

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 12/2021 - 11/2007
14	Messenger RNA (mRNA)IBA 12/2021 - 11/2007
8	PolyaminesIBA 01/2022 - 05/2010
5	Transcription Factors (Transcription Factor)IBA 01/2022 - 02/2008
4	SpermidineIBA 01/2022 - 12/2014
4	Pharmaceutical PreparationsIBA 01/2019 - 08/2009
4	Eflornithine (Ornidyl)FDA Link 11/2018 - 04/2013
4	Phosphotransferases (Kinase)IBA 01/2018 - 01/2010
4	Small Interfering RNA (siRNA)IBA 01/2017 - 09/2014
3	AntigensIBA 01/2022 - 01/2003
3	OsteoprotegerinIBA 01/2020 - 10/2014
3	Protein Isoforms (Isoforms)IBA 01/2019 - 07/2014
3	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 01/2018 - 05/2010
2	hypusineIBA 01/2022 - 01/2018
2	CytokinesIBA 01/2022 - 01/2017
2	Peptides (Polypeptides)IBA 01/2022 - 06/2012
2	Biological ProductsIBA 01/2020 - 12/2011
2	TNF-Related Apoptosis-Inducing LigandIBA 01/2020 - 10/2014
2	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2019 - 06/2015
2	EnzymesIBA 01/2019 - 01/2018
2	Annexin A5IBA 01/2018 - 11/2007
2	CationsIBA 01/2018 - 09/2014
2	LigandsIBA 01/2017 - 03/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016 - 02/2013
2	sepiapterin reductaseIBA 06/2015 - 01/2014
2	PlectinIBA 07/2014 - 01/2003
1	homeobox A1 proteinIBA 01/2022
1	Chimeric Antigen ReceptorsIBA 01/2022
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2022
1	InterleukinsIBA 01/2022
1	Calcibiotic Root Canal SealerIBA 01/2022
1	Peptide Initiation Factors (Initiation Factor)IBA 01/2022
1	cytidylyl-(3'-5')-cytidine (CpC)IBA 01/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020
1	SodiumIBA 01/2020
1	ChemokinesIBA 01/2020
1	Poly I-CIBA 01/2019
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 01/2019
1	NADPH Oxidases (NAD(P)H oxidase)IBA 09/2018
1	Drug CombinationsIBA 01/2018
1	CaspasesIBA 01/2018
1	Harmine (Telepathine)IBA 01/2018
1	GlycosyltransferasesIBA 01/2018
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2018
1	Tyrosine (L-Tyrosine)FDA Link 01/2018
1	Calcium Channels (Calcium Channel)IBA 01/2018
1	CC ChemokinesIBA 01/2017
1	Interleukin-1beta (Interleukin 1 beta)IBA 01/2017
1	Monocyte Chemoattractant ProteinsIBA 01/2017
1	Complementary DNA (cDNA)IBA 01/2017
1	von Willebrand FactorIBA 01/2017
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2017
1	Polysaccharides (Glycans)IBA 02/2016
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 02/2016
1	sialic acid transport proteinsIBA 02/2016
1	Myeloid Ecotropic Viral Integration Site 1 ProteinIBA 02/2016
1	Amino Acids FDA Link 02/2016
1	LeptinIBA 01/2016
1	Triglycerides (Triacylglycerol)IBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 01/2016
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2016
1	Caveolin 1IBA 01/2016
1	SpermineIBA 06/2015
1	N(1)-guanyl-1,7-diaminoheptaneIBA 12/2014
1	deoxyhypusine synthaseIBA 12/2014

Therapy/Procedure

12	Therapeutics 01/2022 - 08/2009
3	Drug Therapy (Chemotherapy) 01/2018 - 08/2013
2	Combined Modality Therapy 06/2015 - 12/2014
1	Immunotherapy 01/2022
1	Radiotherapy 11/2016